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Secondary measures included apathy, quality of life, and cognition.Genome-wide transcriptional profiles were generated from peripheral blood leukocytes sampled at baseline and 3 months following initiation of treatment.
Individual contributor disclosures may be found within the abstracts.Results: We find that offspring receiving low quality maternal care in the early life show peripheral IR in adulthood as suggested by increased levels of insulin, glucose and tryglicerides in comparison with offspring that received high quality maternal care.This state of IR in adulthood is concomitant with increased expression of the mineralocorticoid receptors (MR) in hippocampus and corresponding anxiety-like behavior at the light-dark test in low nurtured offspring.Furthermore, comorbid depression in patients with cognitive impairment appears to accelerate the neurodegenerative process, accelerating conversation to dementia.Our objective was to evaluate the efficacy of memantine augmentation of escitalopram treatment in elderly patients in improving clinical and cognitive outcome.
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Talking about his early life, Pharrell Williams was born on 5 April 1973, in Virginia Beach, Virginia, USA. He is the son of Pharaoh Williams, a handyman, and his wife Carolyn, a teacher. Williams completed his education from Princess Anne High School. Williams began his career as a singer in early 1990s.
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